Book Details

Hardcover: 655 pages
Publisher: Wiley-Blackwell; 2 edition (January 15, 2001)
Language: English
ISBN-10: 0632043598
ISBN-13: 978-0632043590.

Book Description

Harvard Medical School, Boston, MA. Provides a thorough and current review of existing and emerging treatments for diseases of immunologic origin. For researchers and clinicians. Three sections demonstrate how developments can provide treatment strategies for previously incurable diseases. Previous edition: c1996. DNLM: Immunotherapy.

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Book Details

Hardcover: 526 pages
Publisher: Oxford University Press, USA; 1 edition (May 19, 2005)
Language: English
ISBN-10: 0198525761
ISBN-13: 978-0198525769.

Book Description

This is the first book to offer a comprehensive overview of higher-order motor disorders. It introduces new concepts emerging from basic neurosciences and shows how they have impacted on the field of cognitive motor control and led to new vistas for the understanding of Higher-order Motor Disorders far beyond the traditional field of topological diagnosis. It describes in detail a wide range of clinical disorders including those of bimanual co-ordination, apraxia and sensorimotor transformation deficits, motor neglect, anarchic hand syndrome, imitation and utilisation behaviours, action motivational and action monitoring disorders, as well as new approaches to motor cortex plasticity and reorganisation and rehalibitation of complex movement problems. The book reviews the topic, starting with a description of the neuroanatomical, neurobiological and cognitive basis of normal motor behaviours, before moving on to cover the clinical features of the disordered states. The final chapters cover the issues of plastcity and recovery, pharmacological treatments and rehabilitation. This volume will stimulate research and foster new insights into cognitive and motivational motor disorders. With expert contributions from the major international centres in Europe and the Americas his book gives a truly new framework for a complex and confusing field.

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Book Details

Hardcover: 720 pages
Publisher: Elsevier Science; 1 edition (March 15, 1989)
Language: English
ISBN-10: 0444872930
ISBN-13: 978-0444872937.

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Book Details

Paperback: 384 pages
Publisher: Wiley; 1 edition (December 15, 2008)
Language: English
ISBN-10: 0470024909
ISBN-13: 978-0470024904.

Book Description

Anyone who attempts to read genetics or epidemiology research literature needs to understand the essentials of biostatistics. This book, a revised new edition of the successful Essentials of Biostatistics has been written to provide such an understanding to those who have little or no statistical background and who need to keep abreast of new findings in this fast moving field. Unlike many other elementary books on biostatistics, the main focus of this book is to explain basic concepts needed to understand statistical procedures.

This Book:

• Surveys basic statistical methods used in the genetics and epidemiology literature, including maximum likelihood and least squares.
• Introduces methods, such as permutation testing and bootstrapping, that are becoming more widely used in both genetic and epidemiological research.

• Is illustrated throughout with simple examples to clarify the statistical methodology.
• Explains Bayes’ theorem pictorially.
• Features exercises, with answers to alternate questions, enabling use as a course text.

Written at an elementary mathematical level so that readers with high school mathematics will find the content accessible. Graduate students studying genetic epidemiology, researchers and practitioners from genetics, epidemiology, biology, medical research and statistics will find this an invaluable introduction to statistics.

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Book Details

Hardcover: 639 pages
Publisher: Oxford University Press, USA; 1 edition (August 15, 2000)
Language: English
ISBN-10: 0195128303
ISBN-13: 978-0195128307.

Book Description

With the accelerating discovery of human genes, public health professionals are increasingly confronted with a large body of scientific information that will guide public health action. Because the broad mission of public health is to fulfill society’s interest in assuring conditions in which people can be healthy, the integration of new genetic information in public health research, policy and program development is unavoidable. Public health leadership is urgently needed to use genetic information to improve health and prevent disease, and to address ethical, legal and social issues resulting from inappropriate use of such information. In the not too-distant future, disease prevention and health promotion programs will routinely consider whether or not to use genetic information to help target behavioral, medical or environmental intervention activities in order to maximize benefit and minimize costs and harm to individuals. In anticipation of the expected growth at the interface of genetics and public health, this book delineates a framework for the integration of advances in human genetics into public health practice. It provides a comprehensive review of public health genetics, including chapters on important general issues such as newborn and other genetic screening, the delivery of genetic services, and the ethical, legal and social implications of the use of genetics within public health. It also reviews relevant clinical topics, the historical background, cross-cultural aspects, and communication issues. Contributors come from a wide range of fields including epidemiology, biostatistics, health policy and management, health services research, behavioral and social sciences, ethics, law, health economics, and laboratory sciences.

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Book Details

Hardcover: 300 pages
Publisher: Springer; 1 edition (November 13, 2003)
Language: English
ISBN-10: 3540413804
ISBN-13: 978-3540413806.

Book Description

Conformal radiation therapy represents a new challenge for radiation oncologists. It offers the prospect of either increasing the radiation dose to target tissues while delivering a similar dose to organs at risk, or reducing the dose to organs at risk while maintaining the dose to target tissues. First, lymph node areas at risk are established using the available data from pathological examination of surgical specimens and/or pattern of locoregional relapse. Then, based on a three-dimensional description of the anatomical regions where the areas at risk are located, guidelines for the delineation of the clinical target volumes are proposed. The data presented should enable the reader to make appropriate decisions regarding the selection and delineation of the target volumes when confronted with the most frequent tumor types and sites.The book will contribute to paving the way for more effective radiation oncology in the twenty-fClinical Target Volumes in Conformal and Intensity Moduirst century.

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Book Details

Hardcover: 361 pages
Publisher: Wiley-VCH; 1 edition (March 31, 2006)
Language: English
ISBN-10: 3527312528
ISBN-13: 978-3527312528.

Book Description

“There are not so many books on statistical methods focused on genetic epidemiology. This contribution fills a gap with a good selection of topics presented in a concise format that will be useful for biostatisticians starting in the field and geneticists or epidemiologists that want to master the specialized statistics used in genetics.” ISCB NEWS

Covering the latest developments, this advanced textbook introduces the relevant statistical methods applied in this field.

• Provides a concise introduction to genetic fundamentals
• Explains both linkage analysis and association analysis in detail
• Features more than 100 problems and solutions
• Includes a foreword by Robert C. Elston, Director, Division of Genetic and Molecular Epidemiology at the Case Western Reserve University, Cleveland, Ohio.

Written by the prize-winning scientist Andreas Ziegler, President of the German Region of the International Biometric Society, and Inke Koenig, who contributes several years of teaching experience, this is an ideal text for all epidemiologists, geneticists, statistics specialists, biomathematicians, and graduate students.

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Book Details

Hardcover: 311 pages
Publisher: Springer; 1 edition (October 18, 2007)
Language: English
ISBN-10: 0387707646
ISBN-13: 978-0387707648.

Book Description

This book provides an overview of the recent advances in the genetics of respiratory control in health and disease. The objective of the book is to bring together top-level contributions on all aspects of the genetics of respiratory control. These include molecular aspects of respiratory neurodevelopment from embryonic to postnatal life, molecular biology of human respiratory control disorders, and interactions between genetics and plasticity in respiratory control. The book will also show how combined studies in humans and mouse models have helped to improve our understanding of the mechanisms that underlie genetically determined respiratory control disorders with the goal of developing new therapeutic interventions.

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Book Details

Hardcover: 168 pages
Publisher: Springer; 1 edition (November 18, 2004)
Language: English
ISBN-10: 3540003452
ISBN-13: 978-3540003458.

Book Description

Since the incidence of skin neoplasms is constantly increasing as the population ages, there is a need for a monograph about radiation treatment of skin neoplasms and diseases. Excellent cosmetic and functional results can be shown with this treatment modality. This book comprehensively examines the indications for radiation therapy of cutaneous cancers, pre-cancerous lesions and benign dermatological disorders. The monograph provides concise introduction to physical and radiobiological principles, selection of radiation factors, dose definitions, as well as radiation reactions and risk assessments. Specific indications for radiotherapy of cutaneous neoplasms and radiation protection measures are discussed. Topics include radiation therapy of basal cell carcinoma, squamous cell carcinoma, lymphomas, Kaposi’s sarcoma, Lentigo maligna melanoma, and Merkel cell tumor. A separate chapter discusses the skin reactions after nuclear accidents. Major scientific publications of the past 10 years are reviewed.

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Book Details

Hardcover: 408 pages
Publisher: CRC Press; 1 edition (October 2, 1991)
Language: English
ISBN-10: 0849364027
ISBN-13: 978-0849364020.

Book Description

Bone Marrow Processing and Purging: A Practical Guide provides an up-to-date practical guide to the major ex vivo procedures associated with bone marrow transplantation. Previously, this information was communicated primarily by word of mouth; now experts in the field present detailed descriptions and evaluations of methods for marrow harvesting, evaluation (including tumor infiltration, flow cytometric analysis, and colony assays), comparative methods for automated nucleated cell separation and enumeration, tumor cell purging, T cell depletion, stem cell selection, gene transfer, and cytopreservation. Special sections address quality control and FDA regulations. The book provides a unique information source intended for clinicians, researchers, technical staff, transplant nurses, and medical students involved in this rapidly expanding area of medicine.

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