Book Details

Hardcover: 648 pages
Publisher: Informa Healthcare; 1 edition (April 6, 2005)
Language: English
ISBN-10: 0824754484
ISBN-13: 978-0824754488.

Book Description

The first and only source to offer a detailed and authoritative review of every aspect of nasal and sinus disorders in children, this reference provides an impressive collection of reviews on topics ranging from disease mechanisms and immunodefense to diagnosis, medical management, and surgical strategy.

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Book Details

Hardcover: 550 pages
Publisher: Informa Healthcare; 1 edition (April 14, 2004)
Language: English
ISBN-10: 0824748743
ISBN-13: 978-0824748746.

Book Description

The first state-of-the-art book dealing specifically with lung injury induced by oxygen and nitrogen radicals, this detailed treatise discusses molecular, cellular, and mechanistic events leading to pathophysiological outcomes; the role of oxidant species in the induction of these events; and potential therapeutic avenues targeting such molecular pathways. Important issues regarding oxidative stress involvement in the initiation and progression of pulmonary diseases-including diseases caused by occupational and environmental inhalation of toxicants-are discussed in the context of amelioration by antioxidants.

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Book Details

Paperback: 428 pages
Publisher: Cambridge University Press; 1 edition (October 15, 2009)
Language: English
ISBN-10: 0521121167
ISBN-13: 978-0521121163.

Book Description

This reference work describes the routes by which disease causing microorganisms are transmitted and how disease transmission is prevented by disinfection and control of microbial growth. The first part of this book addresses the processes of infectious disease transmission and prevention. The second section specifically deals with the prevention of infectious diseases that are transmitted by water or food. The third part considers disease transmission by aerosols, environmental surfaces and medical devices. The final four chapters describe some essential mechanisms of disinfection. Throughout this volume, experts demonstrate how our ability to model the processes of disease transmission and disinfection helps us understand them.

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Book Details

Hardcover: 296 pages
Publisher: Springer; 1 edition (January 31, 2001)
Language: English
ISBN-10: 0792372689
ISBN-13: 978-0792372684.

Book Description

In recent years much enthusiasm and energy has been directed toward the development of human gene therapies, especially for inherited conditions and cancers. However, current gene transfer technology is limited in its transduction efficiency and ability to permanently and safely correct genomic defects. Thus the promise of gene therapy for these conditions is as yet unrealized. The progression of gene transfer technology will eventually surmount these limitations.

Gene Therapy for Acute and Acquired Diseases includes selected examples of ongoing studies in molecular genetics that have the potential to evolve into human therapies for acute illnesses. These chapters are intended to highlight lesser known applications of gene therapy for acquired disorders. It is expected that human gene therapy trials for these conditions will be forthcoming in the near future, leading to previously unimaginable therapies. Thus, this first-ever book about gene therapy for acute and acquired diseases is intended to serve as a glimpse into the future.

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Book Details

Hardcover: 428 pages
Publisher: Wiley-Interscience; 1 edition (August 3, 2005)
Language: English
ISBN-10: 9780471668275
ISBN-13: 978-0471668275.

Book Description

Antiviral Drug Discovery gives readers a cutting-edge view of how chemical concepts are being mobilized to develop novel approaches that will effectively confront emerging diseases and biowarfare. Among the many topics discussed are smallpox, the Ebola virus, influenza, SARS, arenaviruses and flaviviruses. Each chapter discusses hypothetical strategies for the discovery of relevant antiviral agents, recent findings related to biochemistry or drug discovery, and advances in the further development of established leads in the area. Timely and informative, this book clearly delineates the efforts being made to develop new and effective broad-spectrum antiviral agents.

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Book Details

Hardcover: 276 pages
Publisher: Wiley; 1 edition (October 24, 2006)
Language: English
ISBN-10: 0470016434
ISBN-13: 978-0470016435.

Book Description

Dengue virus is a member of the Flaviviridae family, which includes viruses associated with human diseases such as yellow fever, Japanese encephalitis and hepatitis C. Dengue fever is transmitted by mosquitoes, principally Aedes aegypti. There are four serotypes of dengue virus, of which DENV-2 has been the most prevalent in many recent epidemics. Following primary infection, lifelong immunity develops, preventing repeated assault by the same serotype. However, the non-neutralizing antibodies from a previous infection or maternally acquired antibodies are thought to form complexes with a different serotype during a subsequent infection and cause dengue haemorrhagic fever/dengue shock syndrome, which can be fatal. There is no treatment or vaccine available today that can combat this emerging and uncontrolled disease.

This book features contributions from the world’s leading researchers working on dengue and related flaviviruses who examine the current state of the art in the molecular biology of the dengue virus. Particular emphasis is placed on the structure and function of the virus and the targeting of virus proteins by potential antiviral agents. The pathogenesis of dengue and dengue haemorrhagic fever are discussed in detail, especially the target cells and the specific receptors on these cells, thereby developing a clear overview of host and viral factors that contribute to dengue haemorrhagic fever. Finally, the book reviews the therapeutic options, paying particular attention to ways in which vector, host and environment can play a critical role in the spread of this disease.

With dengue fever and other emerging viral diseases becoming increasingly prevalent around the world, this book provides valuable insight into the virus that causes this disease and potential ways to manage it. It is essential reading for all those working in tropical diseases, public health and virology.

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Book Details

Paperback: 352 pages
Publisher: Wiley-Blackwell; 1 edition (July 7, 2009)
Language: English
ISBN-10: 1573317500
ISBN-13: 978-1573317504.

Book Description

This volume contains the proceedings of the 5th International Conference on Rickettsiae and Rickettsial Diseases, in which an effort is made to address and clarify issues from clinical, diagnostic, epidemiologic, and molecular perspectives that have remained unsolved in the past.

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Book Details

Hardcover: 194 pages
Publisher: Springer; 1 edition (April 18, 2007)
Language: English
ISBN-10: 9780387254425
ISBN-13: 978-0387254425.

Book Description

The book deals with dermatologic diseases involving serious cutaneous malignancies. The sections are organized alphabetically and color-coded. Approximately 40 disease states are discussed with accompanying full-color clinical and microscopic photography. Each entity contains a single clinical photograph accompanied by three photomicrographs detailing the diagnostic features of each case. Subsections detailing disease prognosis are presented in a bullet-style. The pedagogical value of this book is its unique presentation of a variety of dermatologic entities capable of leading to serious medical consequences including death.

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Book Details

Hardcover: 290 pages
Publisher: Springer; 1 edition (October 20, 2008)
Language: English
ISBN-10: 9780387095592
ISBN-13: 978-0387095592.

Book Description

The ease of use of the programs in the application to ever more complex cases of disease and pestilence. The lack of need on the part of the student or modelers of mathematics beyond algebra and the lack of need of any prior computer programming experience. The surprising insights that can be gained from initially simple systems models.

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Book Details

Hardcover: 480 pages
Publisher: Springer; 2nd edition (November 23, 2004)
Language: English
ISBN-10: 9783540425427
ISBN-13: 978-3540425427.

Book Description

This second edition of The Physician’s Guide provides paediatricians and other physicians with a unique aid to help them select the correct diagnosis from a bewildering array of complex clinical and laboratory data. Delay and mistakes in the diagnosis of inherited metabolic diseases may have devastating consequences. The guide, which includes a CD-ROM, describes 298 disorders which have been grouped into 35 chapters according to the type of condition. Within each group of disorders, chapters provide tables of pertinent clinical findings as well as reference and pathological values for crucial metabolites. Relevant metabolic pathways and diagnostic flow charts are included. There are three indices to make the book as user-friendly as possible.

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